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:: Volume 21, Issue 1 (Spring 2024) ::
Sci J Iran Blood Transfus Organ 2024, 21(1): 46-53 Back to browse issues page
Comparison of the effect of natural silk and Chitohem powder on blood clotting time: an in vitro study
F. Owlia , M.H. Akhavan Karbasi , E. Babaei Zarch
Abstract:   (128 Views)
Abstract
Background and Objectives
Uncontrolled post-operative bleeding can lead to several problems and tissue repair disorder indentistry. This study has been conducted to compare the effect of Chitohem and natural silk on the onset of clot formations.

Materials and Methods
This laboratory study was carried out with a dependent parallel design. Three drops of blood were taken from each of 32 participants in the study. Fifty milligram Chitohem and natural silk powder were poured on two blood drops, respectively. The clot formation time was measured for all three groups simultaneously. Duration between pouring powder and starting of clot formation was recorded. Data analysis was performed using paired t-test and repeated measure ANOVA methods using SPSS 17 software.

Results
Participants composed of 20 (62.5%) women and 12 (37.5%) men. The average age of the participants was 43.33 ± 4.08 years. The average time periods of the onset of blood clot formation in Chitohem group, natural silk and control group were 90.97 ± 29.99, 141.97 ± 49.10, and 195.44 ± 58.70 second, respectively. Paired t-test showed the mean time of clot formation was significantly different among groups (p = 0.0001).

Conclusions 
Based on the obtained results, it seems that although effect of “organic natural silk” on coagulation time was less than “Chitohem”, but silk has an acceptable hemostatic effect. The simultaneous use of natural silk and Chitohem can have a synergistic effect.

 
Keywords: Key words: Hemostasis, Blood Clotting, Bleeding
Full-Text [PDF 514 kb]   (46 Downloads) |   |   Full-Text (HTML)  (23 Views)  
Type of Study: Research | Subject: Oral and maxillofacial diseases
Published: 2024/03/29
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Owlia F, Akhavan Karbasi M, Babaei Zarch E. Comparison of the effect of natural silk and Chitohem powder on blood clotting time: an in vitro study. Sci J Iran Blood Transfus Organ 2024; 21 (1) :46-53
URL: http://bloodjournal.ir/article-1-1521-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 21, Issue 1 (Spring 2024) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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